Cent Eur J Nurs Midw 2026, 17(2):2466-2476 | DOI: 10.15452/cejnm.2026.17.0010

Evaluating the effectiveness of selected existential therapies for death anxiety in advanced cancer: a systematic review and meta-analysis

Nurlelasari Harahap, Renidayati, Heppi Sasmita, Tasman, N. Rachmadanur, Welly
Department of Nursing, Poltekkes Kemenkes Padang, Padang, West Sumatra, Indonesia

Aim: To evaluate the effectiveness of selected existential therapies, including Dignity Therapy (DT), Meaning-Centered Psychotherapy (MCP), Logotherapy, and Reminiscence Therapy (RT), in reducing death anxiety among adults with advanced cancer.

Design: A systematic review and meta-analysis of randomized controlled trials (RCTs).

Methods: A comprehensive search of PubMed, ProQuest, and EBSCO databases was conducted for RCTs published between 2018 and July 2025. Eligible studies included adult cancer patients receiving any of the four existential therapies. Data extraction and quality assessment were performed independently by two reviewers. Pooled effect sizes were calculated using a random-effects model, and subgroup analyses were conducted by therapeutic modality.

Results: Nine RCTs involving 821 participants met the inclusion criteria. The pooled overall effect of existential therapies on death anxiety was small and not statistically significant. Subgroup analysis, however, demonstrated that dignity therapy significantly reduced death anxiety compared with control conditions. Other existential therapies showed modest but inconsistent effects.

Conclusion: While existential therapies offer limited overall benefit for reducing death anxiety in advanced cancer, dignity therapy appears to be the most effective intervention. Further research employing comparative designs, more extended follow-up periods, and culturally adapted approaches is recommended to optimize psychosocial care for terminally ill patients.

Klíčová slova: advanced cancer, death anxiety, dignity therapy, existential therapy, logotherapy, meaning-centered psychotherapy, palliative care, reminiscence therapy

Vloženo: 17. červenec 2025; Revidováno: 4. březen 2026; Přijato: 5. březen 2026; Zveřejněno: 5. červen 2026  Zobrazit citaci

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Harahap N, Renidayati, Sasmita H, Tasman, Rachmadanur N, Welly. Evaluating the effectiveness of selected existential therapies for death anxiety in advanced cancer: a systematic review and meta-analysis. Central European Journal of Nursing and Midwifery. 2026;17(2):2466-2476. doi: 10.15452/cejnm.2026.17.0010.
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